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The Download: “reprogramming” aging, and the hidden sense of interoception

The Download: “reprogramming” aging, and the hidden sense of interoception

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Why “reprogramming” is the buzziest approach to reversing aging right now Earlier this week, Life Biosciences, a biotech company focused on reversing...

Why “reprogramming” is the buzziest approach to reversing aging right now

Why “reprogramming” is the buzziest approach to reversing aging right now

Earlier this week, Life Biosciences, a biotech company focused on reversing age-related diseases, announced that it had dosed its first volunteer. A person with glaucoma has had an experimental treatment injected straight into their eyeball. The idea is to try to treat the disease—which can cause...

Job titles of the future: Nature’s drug designer

Job titles of the future: Nature’s drug designer

In 2018, after nearly two decades working in Big Pharma, chemist Tim Cernak was ready to put his skills to a new use.  For Merck, he’d developed precision therapies for cancer, HIV, and diabetes that could target disease while minimizing harm to healthy cells. But as a lifelong nature lover,...

The “steroid olympics” were a circus—and a window into our culture

The “steroid olympics” were a circus—and a window into our culture

Testosterone. Methenolone. Nandrolone. Human growth hormone and EPO. Meldonium, modafinil, and mixed amphetamine salts. Clomiphene, anastrozole, levothyroxine, and liothyronine. Patches and capsules, creams and pills. A whole galaxy of steroids, metabolic modulators, and synthetic hormones coursing...

Lego Batman - Un easter egg Commodore 64 BASIC caché dedans

Lego Batman - Un easter egg Commodore 64 BASIC caché dedans

Cabel Sasser, le boss de Panic Inc. (les gars derrière Coda, Nova et la fameuse Playdate ), vient de tomber sur un easter egg complètement génial dans LEGO Batman: Legacy of the Dark Knight, le jeu sorti fin mai 2026. Et ce qu'il a découvert, c'est un petit programme Commodore 64 en BASIC affiché à...

The Download: whole-body rejuvenation drugs and five things to know about AI

The Download: whole-body rejuvenation drugs and five things to know about AI

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. David Sinclair plans to test whole-body rejuvenation drugs in the XPrize competition The outspoken longevity scientist David Sinclair has predicted...

David Sinclair plans to test whole-body rejuvenation drugs in the XPrize competition

The outspoken longevity scientist David Sinclair has been predicting that one day, you’ll go to the doctor and get a prescription that will make you 10 years younger. Now MIT Technology Review has learned that he has plans to launch human tests of an oral “reprogramming” drug as part of...